Article
The Primary Cilium is a Microtubule-Driven Electrical Antenna. The Case of Renal Epithelial Cells
2022-02-23
Abstract excerpt
The primary cilium is a non-motile sensory organelle that acts as a transducer of environmental cues into cellular responses. It comprises an axoneme, which is a core of microtubules (MTs), coated by a specialized membrane populated by receptors and a high density of ion channels. Dysfunctional primary cilia generate several diseases known as ciliopathies. However, the nature of ciliary signaling remains largely u...
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Identifiers and source
- Literature Corpus work
- 00adedd4-5b1f-5dcf-8b45-7a743b62ac3e
- DOI
- 10.21203/rs.3.rs-1346209/v1