Article

Identification and characterization of novel Bovine Leukemia Virus (BLV) antisense transcripts reveals their constitutive expression in leukemic and pre-leukemic clones

2016-02-09

Abstract excerpt

Bovine Leukemia Virus (BLV) is a deltaretrovirus closely related to the Human T-cell leukemia virus-1 (HTLV-1). Cattle are the natural host of BLV where it integrates into B-cells and produces a lifelong infection. Most infected animals remain asymptomatic but following a protracted latency period about ∽5% develop an aggressive leukemia/lymphoma, mirroring the disease trajectory of HTLV-1. The 5’LTRs of both the...

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Literature Corpus work: 007bedbd-6529-5280-b6be-bfced331ce84
DOI: 10.1101/039255

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