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Whole-transcriptome analysis of BLV-infected cows reveals downregulation of immune response genes in high proviral loads cows

2024-12-23

Abstract excerpt

Bovine leukemia virus (BLV) is a retrovirus that infects cattle, causing bovine enzootic leukosis, a chronic disease characterized by the proliferation of infected B cells. BLV proviral load (PVL) is a key determinant of disease progression and transmission risk. Cattle can exhibit distinct phenotypes of low PVL (LPVL) or high PVL (HPVL), which remain stable throughout their lifetime. Differential expression analy...

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Literature Corpus work
2ffac9ff-79c2-5ab1-bcda-e004bf88ab72
DOI
10.1101/2024.12.23.627929
Open publication

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Whole-transcriptome analysis of BLV-infected cows reveals downregulation of immune response genes in high proviral loads cowsDOI 10.1101/2024.12.23.627929
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