Article

Functional analysis of promoter element 2 within the viral polymerase gene of an emerging paramyxovirus, Sosuga virus

2025-01-15

Abstract excerpt

Paramyxovirus genomes carry bipartite promoters at the 3’ ends of both their genome and antigenome, thereby initiating RNA synthesis, which requires the viral polymerase to recognize two elements: the primary promoter element 1 (PE1) and the secondary promoter element 2 (PE2). We have previously shown that the antigenomic PE2 (agPE2) in many viruses in the Rubulavirinae subfamily is located within the coding regi...

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Literature Corpus work: 007b27b1-873e-50e8-a671-3f21860c96c7
DOI: 10.1101/2025.01.13.632789

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