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Noncanonical P gene mRNA editing in Cedar virus generates a V-like protein that is required for efficient virion production

2026-03-01

Abstract excerpt

Highly pathogenic Hendra and Nipah viruses encode accessory P gene products (C, V and W) that antagonize innate immunity and contribute to pathogenicity. Cedar virus (CedV), an apathogenic bat-borne henipavirus, is presumed to lack P gene mRNA editing and therefore is unable to express V and W proteins. Here, we identify CedV peptides originating from a frameshifted P gene open reading frame and demonstrate a prev...

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Literature Corpus work
97e7bbc1-b793-5a64-a096-82a6f402f191
DOI
10.64898/2026.02.27.708548
Open publication

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Noncanonical P gene mRNA editing in Cedar virus generates a V-like protein that is required for efficient virion productionDOI 10.64898/2026.02.27.708548
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