Article
Controlling wireframe DNA origami nuclease degradation with minor groove binders
2020-05-27
Abstract excerpt
Virus-like DNA nanoparticles have emerged as promising vaccine and gene delivery platforms due to their programmable nature that offers independent control over size, shape, and functionalization. However, as biodegradable materials, their utility for specific therapeutic indications depends on their structural integrity during biodistribution to efficiently target cells, tissues, or organs. Here, we explore rever...
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Identifiers and source
- Literature Corpus work
- 00546ab4-251d-55db-a348-2dd4ae60c18c
- DOI
- 10.1101/2020.05.24.110783