Article

SLC26A2-mediated sulfate metabolism is essential for the tooth development

2023-04-02

Abstract excerpt

The sulfate transporter gene SLC26A2 is responsible for diastrophic dysplasia, which represents skeletal dysplasia in humans. This highlights the importance of sulfate metabolism in skeletal formation. SLC26A2-related chondrodysplasia is also known to exhibit abnormalities in craniofacial and tooth development. Although the function of SLC26A2 in mammals has been investigated using genetic mouse models, the essent...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 00239ae0-d48c-56b4-85b9-e7a193fb79d4
DOI: 10.1101/2023.03.30.534919

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SLC26A2-mediated sulfate metabolism is essential for the tooth developmentDOI 10.1101/2023.03.30.534919Read

A diastrophic dysplasia sulfate transporter (SLC26A2) mutant mouse: morphological and biochemical characterization of the resulting chondrodysplasia phenotype.Semantic proximity Read

SLC26A2 (diastrophic dysplasia sulfate transporter) is expressed in developing and mature cartilage but also in other tissues and cell types.Semantic proximity Read

Roles of heparan sulfate sulfation in dentinogenesis.Semantic proximity Read

Mutations in the diastrophic dysplasia sulfate transporter (DTDST) gene (SLC26A2): 22 novel mutations, mutation review, associated skeletal phenotypes, and diagnostic relevance.Semantic proximity Read

Dysplastic spondylolysis is caused by mutations in the diastrophic dysplasia sulfate transporter gene.Semantic proximity Read

Mutation in SSUH2 Causes Autosomal-Dominant Dentin Dysplasia Type I.Semantic proximity Read

Genetics and pathophysiology of mammalian sulfate biology.Semantic proximity Read

Skeletal Dysplasias Caused by Sulfation Defects.Semantic proximity Read

The odontoblastic differentiation of dental mesenchymal stem cells: molecular regulation mechanism and related genetic syndromesSemantic proximity Read

Dental Follicle Cells Participate in Tooth Eruption via the RUNX2-MiR-31-SATB2 Loop.Semantic proximity Read

SLC10A7 mutations cause a skeletal dysplasia with amelogenesis imperfecta mediated by GAG biosynthesis defects.Semantic proximity Read

Phenotypic characterization of Slc26a2 mutant mice reveals a multifactorial etiology of spondylolysis.Semantic proximity Read