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Article

Oxidative stress and motor neurone disease.

Brain pathology (Zurich, Switzerland) - 1 Jan 1999

Cookson M R, Shaw P J

Abstract excerpt

The effects of oxidative stress within post mitotic cells such as neurones may be cumulative, and injury by free radical species is a major potential cause of the age-related deterioration in neuronal function seen in several neurodegenerative diseases. There is strong evidence that oxidative stress plays an important role in the pathogenesis of motor neurone disease (MND). Point mutations in the antioxidant...

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Source

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Identifiers

PMID: 9989458
DOI: 10.1111/j.1750-3639.1999.tb00217.x
PMCID: PMC8098266

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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