Article
Genetics of complex human diseases: genome screening, association studies and fine mapping.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Nov 1998
Xu J, Wiesch D G, Meyers D A
Abstract excerpt
Positional cloning has been applied successfully to many Mendelian disorders. Because of the public health significance, there is strong interest in mapping susceptibility genes for common disorders, such as asthma and allergy, that have a genetic component. Genome-wide screening has been very useful in detecting regions of the genome likely to contain susceptibility genes. There are multiple chromosomal regions...
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