No chromosomal instability in offspring of survivors of childhood malignancy.

doi:10.1016/s0165-4608(98)00146-0

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Article

No chromosomal instability in offspring of survivors of childhood malignancy.

Cancer genetics and cytogenetics - 1 Feb 1999

Bajnóczky K, Khezri S, Kajtár P, Szücs R, Kosztolányi G, Méhes K

Abstract excerpt

Chromosomal instability was examined in 20 apparently healthy children of survivors of childhood malignancy. As compared to controls, no increase of spontaneous or bleomycin-induced aberrations (including gaps, breaks, sister chromatid exchanges, pulverization, and premature centromere divisions)...

Topics

Bleomycin
Centromere
Child
Chromosome Aberrations
Female
Genetic Predisposition to Disease
Humans
Karyotyping
Leukemia
Lymphoma
Male
Neoplasms
Nuclear Family
Sister Chromatid Exchange
Survivors

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