Article
Clinical and genetic studies on 12 preaxial polydactyly families and refinement of the localisation of the gene responsible to a 1.9 cM region on chromosome 7q36.
Journal of medical genetics - 1 Jan 1999
Zguricas J, Heus H, Morales-Peralta E, Breedveld G, Kuyt B, Mumcu E F, Bakker W, Akarsu N, Kay S P, Hovius S E, Heredero-Baute L, Oostra B A, Heutink P
Abstract excerpt
Polydactyly is the most frequently observed congenital hand malformation with a prevalence between 5 and 19 per 10000 live births. It can occur as an isolated disorder, in association with other hand/foot malformations, or as a part of a syndrome, and is usually inherited as an autosomal dominant trait. According to its anatomical location, polydactyly can be generally subdivided into pre- and postaxial forms....
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