Article
YNT20, a bypass suppressor of yme1 yme2, encodes a putative 3'-5' exonuclease localized in mitochondria of Saccharomyces cerevisiae.
Current genetics - 1 Jan 1999
Hanekamp T, Thorsness P E
Abstract excerpt
Mutation of YME genes in yeast results in a high rate of mitochondrial DNA escape to the nucleus. The synthetic respiratory growth defect of yme1 yme2 yeast strains is suppressed by recessive mutations in YNT20. Inactivation of YNT20 creates a cold-sensitive respiratory growth defect that is more...
Topics
- ATP-Dependent Proteases
- Adenosine Triphosphatases
- Amino Acid Sequence
- Base Sequence
- Chromosome Mapping
- Cloning, Molecular
- DNA Primers
- DNA, Mitochondrial
- Exodeoxyribonuclease V
- Exodeoxyribonucleases
- Genes, Fungal
- Mitochondria
- Molecular Sequence Data
- Mutation
- Phenotype
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Amino Acid