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Article

Nuclear mutations in Saccharomyces cerevisiae that affect the escape of DNA from mitochondria to the nucleus.

Genetics - 1 May 1993

Thorsness P E, Fox T D

Abstract excerpt

We have inserted a yeast nuclear DNA fragment bearing the TRP1 gene and its associated origin of DNA replication, ARS1, into the functional mitochondrial chromosome of a strain carrying a chromosomal trp1 deletion. TRP1 was not phenotypically expressed within the organelle. However, this Trp- strain readily gave rise to respiratory competent Trp+ clones that contained the TRP1/ARS1 fragment, associated with...

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Identifiers

PMID: 8514129
DOI: 10.1093/genetics/134.1.21
PMCID: PMC1205423

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Source receipt: pubmed, retrieved 7 Sept 2026.

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