Article
Brain stem MRI signal abnormalities in CADASIL.
Stroke - 1 Feb 1999
Chabriat H, Mrissa R, Levy C, Vahedi K, Taillia H, Iba-Zizen M T, Joutel A, Tournier-Lasserve E, Bousser M G
Abstract excerpt
BACKGROUND: We recently showed that the severity of MRI signal abnormalities increases with age in CADASIL, an arteriopathy due to mutations of notch 3 gene on chromosome 19. Previous results also suggest that the various hemispheric subcortical areas have a different vulnerability to ischemia in...
Topics
- Brain Stem
- Cerebral Arteries
- Cerebral Infarction
- Chromosome Aberrations
- Chromosome Disorders
- Chromosomes, Human, Pair 19
- Humans
- Leukoencephalopathy, Progressive Multifocal
- Magnetic Resonance Imaging
- Middle Aged
- Mutation
- Proto-Oncogene Proteins
- Receptors, Cell Surface
