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Article

Analysis of a very large trinucleotide repeat in a patient with juvenile Huntington's disease.

Neurology - 15 Jan 1999

Nance M A, Mathias-Hagen V, Breningstall G, Wick M J, McGlennen R C

Abstract excerpt

A patient with juvenile Huntington's disease (HD) of probable maternal inheritance is reported. The expanded IT-15 allele was only detected with the use of modified PCR and Southern transfer techniques, which showed a CAG trinucleotide repeat expansion of approximately 250 repeats-the largest CAG...

Topics

Adolescent
Age of Onset
Alleles
Blotting, Southern
Humans
Huntington Disease
Male
Polymerase Chain Reaction
Trinucleotide Repeats

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9932964
DOI: 10.1212/wnl.52.2.392

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9932964-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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