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Article

Genetic analysis of hook, a gene required for endocytic trafficking in drosophila.

Genetics - 1 Feb 1999

Krämer H, Phistry M

Abstract excerpt

The Drosophila hook gene encodes a novel component of the endocytic compartment. Previously identified hook alleles, which still expressed truncated Hook proteins, affected the accumulation of internalized transmembrane ligands into multivesicular bodies (MVBs). To determine the hook null phenotype, we isolated nine new hook alleles on the basis of their characteristic hooked-bristle phenotype. At least one of...

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Identifiers

PMID: 9927460
DOI: 10.1093/genetics/151.2.675
PMCID: PMC1460498

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