Article
Early on-treatment viral load and baseline METAVIR score: improved prediction of sustained virological response in HCV genotype 1 patients.
Antiviral therapy - 1 Jan 2012
Crawford Darrell H G, Dore Gregory J, Sievert William, Cheng Wendy S C, Weltman Martin, McCaughan Geoffrey, Rawlinson William, Marks Philippa S, Yoshihara Motoko, Rizkalla Bishoy, Roberts Stuart K
Abstract excerpt
BACKGROUND: On-treatment HCV viral load during early therapy with pegylated interferon (PEG-IFN) and ribavirin is highly predictive of sustained virological response (SVR). We sought to provide further refinement of this prediction through an extensive evaluation of the effect of HCV viral loads at weeks 4, 8 and 12 on SVR, including analysis by liver disease stage grouping. METHODS: A total of 309 patients with...
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