Article
Knockout mouse model and gametogenic failure.
Molecular and cellular endocrinology - 25 Oct 1998
Grootegoed J A, Baarends W M, Roest H P, Hoeijmakers J H
Abstract excerpt
To evaluate the function of a defined gene in gametogenesis, exciting opportunities are offered by the introduction of techniques to generate knockout mice. In this short article, we briefly describe a few gene knockout mouse models, which show a phenotype that involves impairment of gametogenesi...
Topics
- Animals
- Female
- Gene Expression
- Infertility, Male
- Ligases
- Male
- Mice
- Mice, Knockout
- Oogenesis
- Phenotype
- Spermatogenesis
- Ubiquitin-Conjugating Enzymes
- Ubiquitins