Trimodal distribution of HbS levels in sickle heterozygotes--an useful predictor of the alpha-genotype for population screening.

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Article

Trimodal distribution of HbS levels in sickle heterozygotes--an useful predictor of the alpha-genotype for population screening.

The Indian journal of medical research - 1 Dec 1998

Mukherjee M B, Surve R, Tamankar A, Colah R, Mohanty D

Abstract excerpt

The trimodal distribution of HbS levels in sickle heterozygotes has been used as an indirect approach to determine the prevalence of alpha-thalassaemia in different population groups. We used this approach to predict the alpha-genotypes of 124 sickle cell heterozygotes where the HbS concentration...

Topics

Adolescent
Adult
Anemia, Sickle Cell
Child
Female
Genetic Testing
Genotype
Hemoglobin, Sickle
Heterozygote
Humans
India
Male
Middle Aged
Predictive Value of Tests
Prevalence
alpha-Thalassemia

Source

Open in PubMed

Identifiers

PMID: 9919012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9919012-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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