Article
Prevalence and molecular characterization of alpha-thalassemia syndromes among Indians.
Genetic testing - 1 Jun 2008
Nadkarni Anita, Phanasgaonkar Supriya, Colah Roshan, Mohanty Dipika, Ghosh Kanjaksha
Abstract excerpt
OBJECTIVE: This study was undertaken to determine the prevalence and molecular basis of alpha-thalassemia in the Indian population and its implications in genetic counseling and prenatal diagnosis. METHODS: 1253 random samples were screened for hemoglobinopathies. Red cell indices were measured on the Sysmex K 1000 cell counter; HbA2 and HbF levels were quantitated using high performance liquid chromotography...
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