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Brain-Derived Neurotrophic Factor/Tyrosine Kinase B Signaling Regulates Human Trophoblast Growth in an in Vivo Animal Model of Ectopic Pregnancy

14 Jan 2011

Abstract excerpt

Although medical treatment of unruptured ectopic pregnancy using methotrexate has been established, development of more potent and safer medical treatment is needed due to limited indications and side effects of methotrexate. Brain-derived neurotrophic factor (BDNF) signals through its receptor tyrosine kinase B (TrkB) to regulate the growth of malignant trophoblastic, choriocarcinoma cell. We investigated...

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PMID: 21239439
DOI: 10.1210/en.2010-1124

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Brain-Derived Neurotrophic Factor/Tyrosine Kinase B Signaling Regulates Human Trophoblast Growth in an in Vivo Animal Model of Ectopic PregnancyPMID 21239439Read ↗

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