Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Vascular Endothelial Growth Factor Antagonist Is Produced by the Human Placenta and Released into the Maternal Circulation1

1 Dec 1998

Abstract excerpt

Vascular endothelial growth factor (VEGF) is a potent secreted factor that promotes angiogenesis and maintains the integrity of the endothelium. Levels of VEGF are increased in many tumors and are elevated in women with pre-eclampsia, a serious disease of pregnancy. Here we show by in situ hybridization that the trophoblast contains the mRNA encoding a soluble version of the VEGF receptor known as Flt-1 (sFlt-1:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis and VEGF in Cancer
Share to Kruppel-like factors research
Share to Pregnancy and preeclampsia studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9828203
DOI: 10.1095/biolreprod59.6.1540

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Vascular Endothelial Growth Factor Antagonist Is Produced by the Human Placenta and Released into the Maternal Circulation1PMID 9828203Read ↗

Evidence for the existence of a novel pregnancy-associated soluble variant of the vascular endothelial growth factor receptor, Flt-1Semantic proximity Read ↗

Alternative Splicing of Vascular Endothelial Growth Factor (VEGF)-R1 (FLT-1) pre-mRNA Is Important for the Regulation of VEGF ActivitySemantic proximity Read ↗

Alternative Splicing of Vascular Endothelial Growth Factor (VEGF)-R1 (FLT-1) pre-mRNA Is Important for the Regulation of VEGF ActivitySemantic proximity Read ↗

A Novel Human-Specific Soluble Vascular Endothelial Growth Factor Receptor 1Semantic proximity Read ↗

Preeclampsia and Soluble fms-Like Tyrosine Kinase 1Semantic proximity Read ↗

The vascular endothelial growth factor family in adverse pregnancy outcomesSemantic proximity Read ↗

Soluble flt‐1 and the angiopoietins in the development and regulation of placental vasculature*Semantic proximity Read ↗

Imbalances in circulating angiogenic factors in the pathophysiology of preeclampsia and related disordersSemantic proximity Read ↗

Expression of Placental FLT1 Transcript Variants Relates to Both Gestational Hypertensive Disease and Fetal GrowthSemantic proximity Read ↗

Molecular and functional diversity of vascular endothelial growth factors.Semantic proximity Read ↗

An unexpected tail of VEGF and PlGF in pre-eclampsiaSemantic proximity Read ↗

Placenta Growth Factor: Potential Role in PregnancySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.