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Article

Shark complement: an assessment

1 Dec 1998

Abstract excerpt

The classical (CCP) and alternative (ACP) pathways of complement activation have been established for the nurse shark (Ginglymostoma cirratum). The isolation of a cDNA clone encoding a mannan-binding protein-associated serine protease (MASP)-1-like protein from the Japanese dogfish (Triakis scyllia) suggests the presence of a lectin pathway. The CCP consists of six functionally distinct components: C1n, C2n, C3n,...

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PMID: 9914903
DOI: 10.1111/j.1600-065x.1998.tb01253.x

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