Article
Increased susceptibility of thymocytes to apoptosis in mice lacking AIM, a novel murine macrophage-derived soluble factor belonging to the scavenger receptor cysteine-rich domain superfamily.
The Journal of experimental medicine - 18 Jan 1999
Miyazaki T, Hirokami Y, Matsuhashi N, Takatsuka H, Naito M
Abstract excerpt
Apoptosis of cells must be regulated both positively and negatively in response to a variety of stimuli in the body. Various environmental stresses are known to initiate apoptosis via differential signal transduction cascades. However, induction of signals that may inhibit apoptosis is poorly und...
Topics
- Amino Acid Sequence
- Animals
- Antigens, CD
- Apoptosis
- Apoptosis Regulatory Proteins
- Cell Survival
- Cells, Cultured
- Cloning, Molecular
- Flow Cytometry
- Gene Expression Regulation
- In Situ Hybridization
- Macrophages
- Membrane Proteins
- Mice
- Mice, Knockout