Article
p53 mutations and p53, Waf-1, Bax and Bcl-2 expression in field cancerization of the head and neck.
Anticancer research - 1 Jan 2000
Lavieille J P, Gazzeri S, Riva C, Reyt E, Brambilla C, Brambilla E
Abstract excerpt
Squamous cell carcinomas of the Head and Neck (SCCHN) are related to carcinogens and proceed through multiple genetic and morphological steps. The aim of this study was to establish the status of p53 gene and p53-regulated proteins (Bax, Bcl-2 and Waf-1) expression in head and neck simultaneous p...
Topics
- Alcoholism
- Carcinoma in Situ
- Carcinoma, Squamous Cell
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclins
- Exons
- Gene Expression Regulation, Neoplastic
- Genes, p53
- Head and Neck Neoplasms
- Humans
- Hyperplasia
- Mucous Membrane
- Mutation
- Neoplasm Invasiveness
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Precancerous Conditions
- Proto-Oncogene Proteins