Article
Essential role of the dynamin pleckstrin homology domain in receptor-mediated endocytosis.
Molecular and cellular biology - 1 Feb 1999
Achiriloaie M, Barylko B, Albanesi J P
Abstract excerpt
Pleckstrin homology (PH) domains are found in numerous membrane-associated proteins and have been implicated in the mediation of protein-protein and protein-phospholipid interactions. Dynamin, a GTPase required for clathrin-dependent endocytosis, contains a PH domain which binds to phosphoinositi...
Topics
- Animals
- Binding Sites
- Blood Proteins
- COS Cells
- Dynamins
- Endocytosis
- GTP Phosphohydrolases
- Gene Expression
- Mutation
- Phosphatidylinositol 4,5-Diphosphate
- Phosphoproteins
- Rats
- Recombinant Proteins
- Transfection
- Transferrin