Widespread integration and survival of adult-derived neural progenitor cells in the developing optic retina.

doi:10.1006/mcne.1998.0721

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Article

Widespread integration and survival of adult-derived neural progenitor cells in the developing optic retina.

Molecular and cellular neurosciences - 1 Dec 1998

Takahashi M, Palmer T D, Takahashi J, Gage F H

Abstract excerpt

Adult rat hippocampus-derived neural progenitor cells (AHPC) show considerable adaptability following grafting to several brain regions. To evaluate the plasticity of AHPCs within the optic retina, retrovirally engineered AHPCs were grafted into the vitreous cavity of the adult and newborn rat ey...

Topics

Age Factors
Animals
Antineoplastic Agents
Brain Tissue Transplantation
Cell Differentiation
Cell Survival
Fibroblasts
Genes, Reporter
Graft Survival
Hippocampus
Neurons
Phenotype
Photoreceptor Cells, Vertebrate
Rats
Rats, Inbred F344
Retinal Ganglion Cells
Stem Cell Transplantation
Stem Cells

Source

Open in PubMed

Identifiers

PMID: 9888988
DOI: 10.1006/mcne.1998.0721

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9888988-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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