Article
The Haemophilus influenzae Hap serine protease promotes adherence and microcolony formation, potentiated by a soluble host protein.
Molecular cell - 1 Dec 1998
Hendrixson D R, St Geme J W
Abstract excerpt
Haemophilus influenzae initiates infection by colonizing the upper respiratory mucosa. The process of colonization involves adherence to epithelium and evasion of host immunity. In this study, we examined the H. influenzae Hap adhesin, which has serine protease activity and undergoes autoproteoly...
Topics
- Bacterial Adhesion
- Bacterial Outer Membrane Proteins
- Binding Sites
- Colony Count, Microbial
- Haemophilus influenzae
- Humans
- Hydrolysis
- Microscopy, Electron, Scanning
- Mutation
- Proteinase Inhibitory Proteins, Secretory
- Proteins
- Serine Endopeptidases
- Tumor Cells, Cultured