Molecular determinants of the interaction between Haemophilus influenzae and human cells.

Abstract excerpt

Haemophilus influenzae is a human-specific pathogen that must colonize the human upper respiratory tract to avoid extinction. On occasion, organisms penetrate the epithelial barrier and cause bacteremic disease or spread within the respiratory tract to produce localized disease. Attachment to host epithelium is fundamental to the process of colonization and to the pathogenesis of disease. Accordingly, H....

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