Article
Virulent aggregates of <i>Streptococcus pyogenes</i> are generated by homophilic protein–protein interactions
1 Sept 2000
Abstract excerpt
Many strains of the important human pathogen Streptococcus pyogenes form aggregates when grown in vitro in liquid medium. The present studies demonstrate that this property is crucial for the adherence, the resistance to phagocytosis and the virulence of S. pyogenes. A conserved sequence of 19 amino acid residues (designated AHP) was identified in surface proteins of common S. pyogenes serotypes. This sequence...
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