[Evaluating genetics and environment in development of obesity].

Abstract excerpt

Previous studies with twins had demonstrated that heredity exerts a definite impact on the development of overweight even more than environmental conditions of nutrition. In recent years studies of molecular genetics in imbred obese mice lead to the discovery of the ob-gene coding for the expression of the ob-protein (leptin) in adipose tissue. Mutation of this gene and also of other genes coding for the...

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