Article
End-stage liver disease without hemochromatosis associated with elevated hepatic iron index.
Journal of hepatology - 1 Aug 1998
Cotler S J, Bronner M P, Press R D, Carlson T H, Perkins J D, Emond M J, Kowdley K V
Abstract excerpt
BACKGROUND/AIMS: The utility of standard diagnostic tests for hereditary hemochromatosis in end-stage liver disease is unknown. A homozygous mutation (Cys 282 Tyr) has been identified in most patients with hereditary hemochromatosis. We examined whether serum iron studies and hepatic iron measure...
Topics
- Female
- Genotype
- HLA Antigens
- Hemochromatosis
- Hemochromatosis Protein
- Histocompatibility Antigens Class I
- Homozygote
- Humans
- Iron
- Liver
- Liver Failure
- Liver Transplantation
- Major Histocompatibility Complex
- Male
- Membrane Proteins
- Point Mutation
- Sensitivity and Specificity
- Transferrin