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Article

Determination of a common genetic variant of luteinizing hormone using DNA hybridization and immunoassays.

Clinical endocrinology - 1 Sept 1998

Nilsson C, Jiang M, Pettersson K, Iitiä A, Mäkelä M, Simonsen H, Easteal S, Herrera R J, Huhtaniemi I

Abstract excerpt

OBJECTIVE: An immunologically anomalous form of LH, due to two point mutations in codons 8 and 15 of the LH beta gene, has previously been described. LH status, i.e. the discrimination between wild-type (WT) and variant (V) LH, is usually determined by immunoassays, which can be unreliable at low serum concentrations of LH. A DNA hybridization assay was therefore developed to score the LH genotype in all...

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Source

Identifiers

PMID: 9861329
DOI: 10.1046/j.1365-2265.1998.00532.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Determination of a common genetic variant of luteinizing hormone using DNA hybridization and immunoassays.PMID 9861329Read ↗

Worldwide frequency of a common genetic variant of luteinizing hormone: an international collaborative research. International Collaborative Research Group.Semantic proximity Read ↗

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Occurrence and biological properties of a common genetic variant of luteinizing hormone.Semantic proximity Read ↗

A common polymorphic allele of the human luteinizing hormone beta-subunit gene: additional mutations and differential function of the promoter sequence.Semantic proximity Read ↗

Disparate response of wild-type and variant forms of LH to GnRH stimulation in individuals heterozygous for the LHbeta variant allele.Semantic proximity Read ↗

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