Cytochrome P4501A1 and glutathione S-transferase M1 genotypes as risk factors for prostate cancer in Japan.

doi:10.1093/jjco/28.11.657

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Article

Cytochrome P4501A1 and glutathione S-transferase M1 genotypes as risk factors for prostate cancer in Japan.

Japanese journal of clinical oncology - 1 Nov 1998

Murata M, Shiraishi T, Fukutome K, Watanabe M, Nagao M, Kubota Y, Ito H, Kawamura J, Yatani R

Abstract excerpt

BACKGROUND: The p53 mutation spectrum of prostate cancers developing in Japan indicates a role for environmental factors. This suggests there might be differences in susceptibility due to genetic polymorphisms in metabolic activation enzyme genes. We analyzed genetic polymorphisms of the xenobiot...

Topics

Aged
Aged, 80 and over
Cytochrome P-450 CYP1A1
Genotype
Glutathione Transferase
Humans
Male
Polymorphism, Genetic
Prostatic Neoplasms
Risk Factors

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