Article
Review of bipolar molecular linkage and association studies.
Current psychiatry reports - 1 Apr 2002
Berrettini Wade
Abstract excerpt
This paper reviews the history of molecular genetic linkage and linkage disequilibrium (LD) or association studies of bipolar disorder (BPD). The topic is introduced with a brief discussion of various genetic concepts, including linkage and linkage disequilibrium. It is emphasized that criteria for declaring linkage must include independent confirmation by multiple groups of investigators. Given that the...
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