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Article

Centrotemporal spikes in families with rolandic epilepsy

1 Dec 1998

Abstract excerpt

OBJECTIVE: To localize a gene predisposing to benign epilepsy of childhood with centrotemporal spikes (BECTS). BACKGROUND: BECTS, or rolandic epilepsy, is the most prevalent idiopathic epilepsy syndrome in childhood. Functional relevant defects in the alpha 4 subunit of the neuronal nicotinic acetylcholine receptor (AChR) have been demonstrated in autosomal dominant nocturnal frontal lobe epilepsy, which, like...

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Identifiers

PMID: 9855510
DOI: 10.1212/wnl.51.6.1608

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