Article
An autosomal dominant genetically heterogeneous variant of rolandic epilepsy and speech disorder.
Epilepsia - 1 Jun 2008
Kugler Steven L, Bali Bhavna, Lieberman Philip, Strug Lisa, Gagnon Bernadine, Murphy Peregrine L, Clarke Tara, Greenberg David A, Pal Deb K
Abstract excerpt
We report a three generation pedigree with 11 of 22 affected with a variant form of rolandic epilepsy, speech impairment, oromotor apraxia, and cognitive deficit. The core features comprised nocturnal rolandic seizures, interictal centrotemporal spike waves with early age of onset and late age of offset. The transmission of the phenotype was consistent with autosomal dominant inheritance, with variable...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.