Article
Autosomal dominant inheritance of centrotemporal sharp waves in rolandic epilepsy families.
Epilepsia - 1 Dec 2007
Bali Bhavna, Kull Lewis L, Strug Lisa J, Clarke Tara, Murphy Peregrine L, Akman Cigdem I, Greenberg David A, Pal Deb K
Abstract excerpt
PURPOSE: Centrotemporal sharp (CTS) waves, the electroencephalogram (EEG) hallmark of rolandic epilepsy, are found in approximately 4% of the childhood population. The inheritance of CTS is presumed autosomal dominant but this is controversial. Previous studies have varied considerably in methodology, especially in the control of bias and confounding. We aimed to test the hypothesis of autosomal dominant...
Topics
- Adolescent
- Cerebral Cortex
- Child
- Chromosome Mapping
- Electroencephalography
- Epilepsy, Rolandic
- Family
- Female
- Functional Laterality
- Genes, Dominant
- Genes, Recessive
- Genetic Linkage
- Genetic Predisposition to Disease