Article
Principles of tissue engineering applied to programmable osteogenesis.
Journal of biomedical materials research - 1 Jan 1998
Brekke J H, Toth J M
Abstract excerpt
This article presents a strategy for design, engineering, and fabrication of a bioresorbable, manufactured bone graft substitute (BGS) device. The approach is based on established precepts of osteogenesis, molecular biology of hyaluronic acid and osteoinductive proteins, and theoretical preforman...
Topics
- Animals
- Biocompatible Materials
- Bone Substitutes
- Bone and Bones
- Cells, Cultured
- Chemical Phenomena
- Chemistry, Physical
- Engineering
- Humans
- Hyaluronic Acid
- Lactic Acid
- Materials Testing
- Microscopy, Electron, Scanning
- Osteoblasts
- Osteogenesis
- Phenotype
- Polyesters
- Polymers
