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Article

Principles of tissue engineering applied to programmable osteogenesis.

Journal of biomedical materials research - 1 Jan 1998

Brekke J H, Toth J M

Abstract excerpt

This article presents a strategy for design, engineering, and fabrication of a bioresorbable, manufactured bone graft substitute (BGS) device. The approach is based on established precepts of osteogenesis, molecular biology of hyaluronic acid and osteoinductive proteins, and theoretical preformance criteria for such a device collated from the literature of 1991 to 1996. Application of this design and engineering...

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Identifiers

PMID: 9855197
DOI: 10.1002/(sici)1097-4636(199824)43:4<380::aid-jbm6>3.0.co;2-d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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