Article
Geometry of artificial ECM: sizes of pores controlling phenotype expression in BMP-induced osteogenesis and chondrogenesis.
Connective tissue research - 1 Jan 2002
Kuboki Yoshinori, Jin Qiming, Kikuchi Masahiro, Mamood Javed, Takita Hiroko
Abstract excerpt
This study aims to elucidate the feasible geometry of the scaffolds in bone and periodontal tissue engineering. Several biomaterials with different geometries are compared in terms of their patterns of ectopic BMP-induced chondrogenesis and osteogenesis. The materials include a honeycomb-shaped hydroxyapatite (HCHAP) with different tunnel sizes, a laser-perforated collagen membrane (LPM), and CPSA bioglass...
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