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Article

Development of silk-based scaffolds for tissue engineering of bone from human adipose-derived stem cells.

Acta biomaterialia - 1 Jul 2012

Correia Cristina, Bhumiratana Sarindr, Yan Le-Ping, Oliveira Ana L, Gimble Jeffrey M, Rockwood Danielle, Kaplan David L, Sousa Rui A, Reis Rui L, Vunjak-Novakovic Gordana

Abstract excerpt

Silk fibroin is a potent alternative to other biodegradable biopolymers for bone tissue engineering (TE), because of its tunable architecture and mechanical properties, and its demonstrated ability to support bone formation both in vitro and in vivo. In this study, we investigated a range of silk scaffolds for bone TE using human adipose-derived stem cells (hASCs), an attractive cell source for engineering...

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Identifiers

PMID: 22421311
DOI: 10.1016/j.actbio.2012.03.019
PMCID: PMC3367114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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