Article
HMG-CoA reductase guides migrating primordial germ cells.
Nature - 3 Dec 1998
Van Doren M, Broihier H T, Moore L A, Lehmann R
Abstract excerpt
The enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase is best known for catalysing a rate-limiting step in cholesterol biosynthesis, but it also participates in the production of a wide variety of other compounds. Some clinical benefits attributed to inhibitors of HMG-CoA reductase...
Topics
- Animals
- Cell Movement
- Cloning, Molecular
- Drosophila
- Gene Expression
- Genes, Insect
- Germ Cells
- Gonads
- Hydroxymethylglutaryl CoA Reductases
- Mesoderm
- Mutation
- Signal Transduction