Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human complement factor H deficiency associated with hemolytic uremic syndrome.

Journal of the American Society of Nephrology : JASN - 1 Dec 1998

Rougier N, Kazatchkine M D, Rougier J P, Fremeaux-Bacchi V, Blouin J, Deschenes G, Soto B, Baudouin V, Pautard B, Proesmans W, Weiss E, Weiss L

Abstract excerpt

This study reports on six cases of deficiency in the human complement regulatory protein Factor H (FH) in the context of an acute renal disease. Five of the cases were observed in children presenting with idiopathic hemolytic uremic syndrome (HUS). Two of the children exhibited a homozygous deficiency characterized by the absence of the 150-kD form of Factor H and the presence, upon immunoblotting, of the 42-kD...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Blotting, Southern

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Blotting, Western

Share to Child, Preschool

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Infant

Share to Multigene Family

Source

Identifiers

PMID: 9848786
DOI: 10.1681/ASN.V9122318

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human complement factor H deficiency associated with hemolytic uremic syndrome.PMID 9848786Read ↗

Heterozygous and Homozygous Factor H Deficiencies Associated with Hemolytic Uremic Syndrome or Membranoproliferative GlomerulonephritisSemantic proximity Read ↗

Complement factor H and hemolytic uremic syndrome.Semantic proximity Read ↗

Hemolytic uremic syndrome due to homozygous factor H deficiency.Semantic proximity Read ↗

Hemolytic Uremic Syndrome: An Example of Insufficient Complement Regulation on Self‐TissueSemantic proximity Read ↗

Familial relapsing haemolytic uraemic syndrome and complement factor H deficiency.Semantic proximity Read ↗

Complement factor H and the hemolytic uremic syndromeSemantic proximity Read ↗

Factor H family proteins: on complement, microbes and human diseases.Semantic proximity Read ↗

Complement regulatory genes and hemolytic uremic syndromes.Semantic proximity Read ↗

Phenotypic expression of factor H mutations in patients with atypical hemolytic uremic syndrome.Semantic proximity Read ↗

Potentiation of complement regulator factor H protects human endothelial cells from complement attack in aHUS seraSemantic proximity Read ↗

A user's guide to the interactive Web database of factor H-associated hemolytic uremic syndrome.Semantic proximity Read ↗

Factor H mutations in hemolytic uremic syndrome cluster in exons 18-20, a domain important for host cell recognition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.