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Differences between human breast cell lines in susceptibility towards growth inhibition by genistein

1 Aug 2001

Abstract excerpt

Genistein is thought to contribute to the putative breast cancer preventive activity of soya. The mechanisms by which it arrests the growth of breast cells are incompletely understood. In order to explore generic features of the modulation of human breast cell growth by genistein, its effects on cell lines MCF-7, ZR-75.1, T47-D, MDA-MB 468, MDA-MB 231 and HBL 100 were compared. Genistein at 1 microM stimulated...

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PMID: 11506505
DOI: 10.1054/bjoc.2001.1980

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