Article
Monoclonal endothelial cells in appetite suppressant-associated pulmonary hypertension.
American journal of respiratory and critical care medicine - 1 Dec 1998
Tuder R M, Radisavljevic Z, Shroyer K R, Polak J M, Voelkel N F
Abstract excerpt
Anorexigens such as aminorex fumarate and dexfenfluramine are associated with the development of severe pulmonary hypertension (PH), which clinically and histopathologically is considered indistinguishable from idiopathic or primary pulmonary hypertension (PPH). For the current study, we asked whether anorexigen-associated PH is characterized by monoclonal pulmonary endothelial cell proliferation (such as in PPH)...
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