Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BMPR2 germline mutations in pulmonary hypertension associated with fenfluramine derivatives

1 Sept 2002

Abstract excerpt

This study investigated whether patients developing pulmonary arterial hypertension (PAH) after exposure to the appetite suppressants fenfluramine and dexfenfluramine have mutations in the bone morphogenetic protein receptor 2 (BMPR2) gene, as reported in primary pulmonary hypertension. BMPR2 was examined for mutations in 33 unrelated patients with sporadic PAH, and in two sisters with PAH, all of whom had taken...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Pulmonary Hypertension Research and Treatments

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 12358323
DOI: 10.1183/09031936.02.01762002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BMPR2 germline mutations in pulmonary hypertension associated with fenfluramine derivativesPMID 12358323Read ↗

Primary pulmonary hypertension after amfepramone (diethylpropion) with BMPR2 mutation.Semantic proximity Read ↗

Bone morphogenetic proteins, genetics and the pathophysiology of primary pulmonary hypertension.Semantic proximity Read ↗

Mutation in the Gene for Bone Morphogenetic Protein Receptor II as a Cause of Primary Pulmonary Hypertension in a Large KindredSemantic proximity Read ↗

Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-β familySemantic proximity Read ↗

Insights into the genetic and molecular basis of primary pulmonary hypertension.Semantic proximity Read ↗

BMPR2 mutations have short lifetime expectancy in primary pulmonary hypertension.Semantic proximity Read ↗

Primary pulmonary hypertension: molecular basis and potential for therapy.Semantic proximity Read ↗

Gene symbol: BMPR2. Disease: Pulmonary hypertension, primary.Semantic proximity Read ↗

Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene.Semantic proximity Read ↗

Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertensionSemantic proximity Read ↗

Idiopathic pulmonary hypertension: what did we learn from genes?Semantic proximity Read ↗

Identification of a novel mutation in the gene for bone morphogenetic protein receptor II in an Israeli patient with familial primary pulmonary hypertension.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.