Article
[Role of apolipoprotein B and lipoprotein lipase gene polymorphism in variability of serum lipid levels].
Vestnik Rossiiskoi akademii meditsinskikh nauk - 1 Jan 1998
Stepanov V A, Puzyrev V P, Tsymbaliuk I V
Abstract excerpt
The serum lipid level is determined by the complex interaction of genetic and environmental factors. The genetic component of this system includes apolipoprotein B (apoB) and lipoprotein lipase (LPL) genes. Three RFLP markers (XbaI, MspI, EcoRI) in the apoB gene and PvuII-RFLP in the LPL gene were genotypes and five lipid traits (fasting plasma levels of total cholesterol, triglycerides, HDL-, LDL-, and VLDL-...
Topics
- Adult
- Alleles
- Apolipoproteins B
- DNA
- DNA Restriction Enzymes
- Deoxyribonucleases, Type II Site-Specific
- Genetic Markers
- Genotype
- Humans
- Lipids
- Lipoprotein Lipase
