Article
Interactions of the human mitochondrial protein import receptor, hTom20, with precursor proteins in vitro reveal pleiotropic specificities and different receptor domain requirements.
The Journal of biological chemistry - 11 Jul 1997
Schleiff E, Shore G C, Goping I S
Abstract excerpt
Tom20 is part of a multiple component, dynamic complex that functions to import specific cytosolic proteins into or through the outer membrane of the mitochondrion. To analyze the contribution of Tom20 to precursor protein recognition, the cytosolic domain of the human mitochondrial import recept...
Topics
- Adenosine Triphosphate
- Antibodies
- Binding Sites
- Carrier Proteins
- Detergents
- Enzyme Precursors
- Ethylmaleimide
- Humans
- In Vitro Techniques
- Ion Channels
- Membrane Proteins
- Membrane Transport Proteins
- Mitochondrial ADP, ATP Translocases
- Mitochondrial Precursor Protein Import Complex Proteins
- Mitochondrial Proteins
- Models, Molecular
- Mutation
- Ornithine Carbamoyltransferase