Article
The cdr2(+) gene encodes a regulator of G2/M progression and cytokinesis in Schizosaccharomyces pombe.
Molecular biology of the cell - 1 Dec 1998
Breeding C S, Hudson J, Balasubramanian M K, Hemmingsen S M, Young P G, Gould K L
Abstract excerpt
Schizosaccharomyces pombe cells respond to nutrient deprivation by altering G2/M cell size control. The G2/M transition is controlled by activation of the cyclin-dependent kinase Cdc2p. Cdc2p activation is regulated both positively and negatively. cdr2(+) was identified in a screen for regulators of mitotic control during nutrient deprivation. We have cloned cdr2(+) and have found that it encodes a putative...
Topics
- ATP-Binding Cassette Transporters
- Amino Acid Sequence
- Base Sequence
- Cell Division
- DNA Primers
- DNA, Fungal
- Fungal Proteins
- G2 Phase
- Gene Expression
- Genes, Fungal
- Mitosis