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Article

Effect of BRCA1 and BRCA2 on the association between breast cancer risk and family history.

Journal of the National Cancer Institute - 2 Dec 1998

Claus E B, Schildkraut J, Iversen E S, Berry D, Parmigiani G

Abstract excerpt

BACKGROUND: The discovery of BRCA1 and BRCA2 has led to a reassessment of the association between family history of breast/ovarian cancer and breast cancer risk after controlling for carrier status for mutations in the BRCA1 and BRCA2 genes. We examined whether family history of breast cancer remains a predictive risk factor for this disease after carrier status for BRCA1 and/or BRCA2 mutations is taken into...

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Source

Identifiers

PMID: 9839523
DOI: 10.1093/jnci/90.23.1824

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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